Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Etoposide is used in dog for Lymphoma rescue protocols. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Etoposide in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: VePesid, Toposar
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 60–100 mg/m2 | q21 days | Variable | Lymphoma rescue protocols | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits topoisomerase II forming DNA-drug-enzyme complex causing double-strand DNA breaks. S and G2 phase specific.
Myelosuppression dose-limiting. Hypotension with rapid IV infusion (infuse over 30-60 min). Oral bioavailability variable. Used in some lymphoma rescue protocols.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Etoposide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.