Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Gemcitabine is used in dog for Transitional cell carcinoma / other carcinomas. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Gemcitabine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Gemzar
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 675–800 mg/kg | 675-800mg/m2 IV over 20 min, q7-14 days | Monitor CBC at nadir (day 7) | Transitional cell carcinoma / other carcinomas | Moderate | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Deoxycytidine analogue that inhibits DNA synthesis by incorporating into DNA and inhibiting ribonucleotide reductase. Masked chain terminator mechanism.
Myelosuppression is dose-limiting. Monitor CBC. May cause pulmonary toxicity and hepatotoxicity. Used in dogs for transitional cell carcinoma and other solid tumors.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Gemcitabine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.