ExoticRx · exoticrx.com/drugs/metoclopramide
US brand names:Reglan
Metoclopramide is dosed at 0.06 mg/kg PO q24h x 7 days in ball pythons, per Divers SJ. Constipation in snakes withttparticular reference to surgical correction in a Burmese python (Python molurus bivittatus). Proc Annu Conf Assoc Rept Amph Vet; 1996:67-69. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.274 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.11 (Miscellaneous Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Dopamine D2 receptor antagonist. Increases GI motility (prokinetic) and acts centrally as an antiemetic at the chemoreceptor trigger zone.
May cause extrapyramidal signs (restlessness, tremors). Contraindicated with GI obstruction or perforation. Avoid concurrent use with phenothiazines.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Metoclopramide CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.01–0.02 mg/kg/hper hour (CRI) | Severe vomiting, CRI for persistent nausea | Strong | Merck/MSD Veterinary Manual, Prokinetic Drugs table (0.01-0.02 mg/kg/h IV infusion) https://www.merckvetmanual.com/multimedia/table/prokinetic-drugs | Higher published regimens: Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) (1-2 mg/kg/day); Today's Veterinary Practice, Management of GI Hypomotility in the Hospitalized Patient (0.5 mg/kg bolus then 2-8 mg/kg/day) — Plumb's 10th ed (held) printed p.867, Metoclopramide monograph spanning p.867-869; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | IV | 0.01–0.02 mg/kg/hper hour (CRI) |
A dog/cat sample is shown here. Cited dosing for all 29 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.01–0.02 mg/kg/h | per hour (CRI) | Strong | Merck/MSD Veterinary Manual, Prokinetic Drugs table (0.01-0.02 mg/kg/h IV infusion) https://www.merckvetmanual.com/multimedia/table/prokinetic-drugs | Higher published regimens: Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) (1-2 mg/kg/day); Today's Veterinary Practice, Management of GI Hypomotility in the Hospitalized Patient (0.5 mg/kg bolus then 2-8 mg/kg/day) — Plumb's 10th ed (held) printed p.867, Metoclopramide monograph spanning p.867-869; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | IV | 0.01–0.02 mg/kg/h | per hour (CRI) |
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Species references:All African Grey Parrot drugsAll African Pygmy Hedgehog drugsAll Ball Python drugsAll Bearded Dragon drugsAll Blue-and-Gold Macaw drugsAll Blue-tongue Skink drugsAll Cat (Domestic) drugsAll Chinchilla drugsAll Corn Snake drugsAll Crested Gecko drugsAll Degu drugsAll Dog (Domestic) drugsAll Dwarf Hamster drugsAll Ferret drugsAll Great Horned Owl drugsAll Guinea Pig drugsAll Harris Hawk drugsAll Horse (Equine) drugsAll Lovebird drugsAll Mouse drugsAll Peregrine Falcon drugsAll Pet Rat drugsAll Rabbit (Domestic) drugsAll Red-eared Slider drugsAll Red-tailed Hawk drugsAll Russian Tortoise drugsAll Sugar Glider drugsAll Sulcata Tortoise drugsAll Umbrella Cockatoo drugs
| Severe vomiting (CRI) |
| Moderate |
| Merck/MSD Veterinary Manual, Prokinetic Drugs table (0.01-0.02 mg/kg/h IV infusion, dogs and cats) https://www.merckvetmanual.com/multimedia/table/prokinetic-drugs | Higher published regimens: Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted); Today's Veterinary Practice, Management of GI Hypomotility in the Hospitalized Patient — Plumb's 10th ed (held) printed p.867, Metoclopramide monograph spanning p.867-869; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Severe vomiting, CRI for persistent nausea
Severe vomiting (CRI)
| Merck/MSD Veterinary Manual, Prokinetic Drugs table (0.01-0.02 mg/kg/h IV infusion, dogs and cats) https://www.merckvetmanual.com/multimedia/table/prokinetic-drugs | Higher published regimens: Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted); Today's Veterinary Practice, Management of GI Hypomotility in the Hospitalized Patient — Plumb's 10th ed (held) printed p.867, Metoclopramide monograph spanning p.867-869; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |