Question 1

What is Metoclopramide used for?

Accepted Answer

Metoclopramide is indicated for: Acute vomiting, CRI, Crop stasis, Gastric reflux, gastroparesis, GI stasis, GI stasis (prokinetic), Nausea, post-operative ileus, Prokinetic, Prokinetic post-procedure, regurgitation, Severe GI stasis (CRI), Severe vomiting, Severe vomiting (CRI), vomiting.

Question 2

What routes can Metoclopramide be administered by?

Accepted Answer

Available routes: PO, SC, IM, IV.

Question 3

Which species have cited Metoclopramide dosing data?

Accepted Answer

Metoclopramide dosing in the ExoticRx formulary covers 9 species: African Grey Parrot, Bearded Dragon, Cat (Domestic), Chinchilla, Dog (Domestic), Ferret, Guinea Pig, Horse (Equine), Rabbit (Domestic).

Question 4

Is Metoclopramide a controlled substance?

Accepted Answer

Metoclopramide is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Metoclopramide?

Accepted Answer

May cause extrapyramidal signs (restlessness, tremors). Contraindicated with GI obstruction or perforation. Avoid concurrent use with phenothiazines.

Question 6

What are the side effects of Metoclopramide?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Metoclopramide: May cause extrapyramidal signs (restlessness, tremors). Contraindicated with GI obstruction or perforation. Avoid concurrent use with phenothiazines.

Question 7

How does Metoclopramide work?

Accepted Answer

Dopamine D2 receptor antagonist. Increases GI motility (prokinetic) and acts centrally as an antiemetic at the chemoreceptor trigger zone.

Question 8

What is the constant rate infusion (CRI) dose for Metoclopramide?

Accepted Answer

Metoclopramide has 2 CRI dose rules in the ExoticRx formulary, covering Cat (Domestic), Dog (Domestic). See the CRI section on this page for routes, dose ranges, and primary-source citations.

Species	Route	Rate	Indication	Evidence	Source
Cat (Domestic)	IV	0.01–0.02 mg/kgper hour (CRI)	Severe vomiting (CRI)	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	IV	0.01–0.02 mg/kgper hour (CRI)	Severe vomiting, CRI for persistent nausea	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Species	Route	Dose	Frequency	Evidence	Source
Cat (Domestic)	IV	0.01–0.02 mg/kg	per hour (CRI)	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	IV	0.01–0.02 mg/kg	per hour (CRI)	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Metoclopramide

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Metoclopramide dosing data (19 dose rules)

Evidence levels across 19 dose rules

Backed by 4 published sources

Constant rate infusion (CRI)

Sample dosing (2 of 19 cited rules)

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