Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lapatinib is dosed at 10–25 mg/kg PO q24h in dogs, per Papich Handbook of Veterinary Drugs, 5th Ed. Lapatinib is used in dogs for Mammary carcinoma (investigational). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Lapatinib in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tykerb
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–25 mg/kg | q24h | Per oncology protocol | Mammary carcinoma (investigational) | Extrapolated | Papich Handbook of Veterinary Drugs, 5th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Dual tyrosine kinase inhibitor of EGFR (ErbB1) and HER2 (ErbB2). Blocks downstream MAPK and PI3K/Akt signaling. Investigational in canine mammary carcinoma.
Experimental in veterinary oncology. Hepatotoxicity, GI toxicity, and cardiac effects possible. Monitor liver enzymes. Limited veterinary data.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Lapatinib dose range in dogs, with cited source references: PO 10–25 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Lapatinib in dogs: PO.
Cited course lengths for Lapatinib in dogs include: Per oncology protocol. Duration depends on the indication — match it to the specific dose rule in the table above.
Lapatinib is indicated in dogs for: Mammary carcinoma (investigational).
These are general warnings for Lapatinib across species; consult the dog dosing table above for species-specific guidance. Experimental in veterinary oncology. Hepatotoxicity, GI toxicity, and cardiac effects possible. Monitor liver enzymes. Limited veterinary data.
Why a species-specific page? Lapatinib pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.