ExoticRx · exoticrx.com/drugs/ketoprofen
US brand names:Ketofen
Ketoprofen is dosed at 2 mg/kg IM SID for 3 days in eastern box turtles, per MacLean RA, Harms CA, Braun-McNeill J. Propofol anesthesia in loggerhead (Caretta caretta) sea turtles. J Wildl Dis. 2008;44:143-150. | Tuttle AD, Papich M, Lewbart GA, et al. Pharmacokinetics of ketoprofen in the green iguana (Iguana iguana) following single intravenous and intramuscular injections. J Zoo Wildl Med. 2006;37:567-570. doi:10.7589/0090-3558-44.1.143 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.253 (2026-08-01).. Verify against current literature before clinical use.
Non-selective COX inhibitor with potential lipoxygenase inhibitory activity. Anti-inflammatory, analgesic, and antipyretic.
Short-term use only (3-5 days). GI ulceration risk. Avoid with other NSAIDs. Not approved for cats in all jurisdictions. Monitor renal function.
Species references:All Cat (Domestic) drugsAll Degu drugsAll Dog (Domestic) drugsAll Eastern Box Turtle drugsAll Green Iguana drugsAll Mouse drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | SC | 1–2 mg/kg | Single dose | Moderate | Tobias KM, Harvey RC and Byarlay JM (2006) A comparison of four methods of analgesia in cats following ovariohysterectomy. Veterinary Anaesthesia and Analgesia 33, 381-389 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.237 (2026-08-01). |
| Dog (Domestic) | SC | 1–2 mg/kg | Single dose | Moderate | Narito T, Sato R, Tomizawa N et al. (2006) Safety of reduced dosage ketoprofen for long term oral administration in dogs. American Journal of Veterinary Research 67, 1115-1120 doi:10.2460/ajvr.67.7.1115 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.237 (2026-08-01). |
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